犬がコロナ陽性者を嗅ぎ分け、将来は空港で活用も 研究
犬は、並外れた嗅覚を生かして、がんやマラリア、てんかんなどの病気を嗅ぎ分けられることがこれまでに分かっている。
英ロンドン大学公衆衛生学・熱帯医学大学院(LSHTM)の研究者らは、新型コロナウイルス検査で陽性と判定された無症状の人から発せられる化学物質のにおいを犬が探知できるかどうか調べた。
新型コロナウイルス検査で陽性を示した人の衣服やマスクのサンプルを集め、訓練した犬で実験したところ、犬はサンプルの82~94%を正しく識別することができた。
論文の査読はまだ終わっていないが、著者らは、いずれは犬が嗅ぎ分けることで入国者を隔離する必要がなくなるかもしれないと期待している。
論文の共同執筆者、LSHTMのジェームズ・ローガン氏は、「重要なポイントは、犬(の嗅ぎ分け)は他の検査より断然速いこと」だと指摘。「犬が(入国者に対して)最初の選別検査を行い、陽性のおそれありと判定された人にPCR検査をすることができるかもしれない」と続けた。
今回の研究に関与していない英ブリストル大学のミック・ベーリー教授(比較免疫学)は、「研究の端緒として極めて重要であり、便利なシステムに発展する可能性がある」と述べた一方、「犬が無症状の新型コロナウイルス感染者を、空港や駅で確実に探知できると確信できるようになるには、もっと検証が必要だ」と指摘した。【翻訳編集AFPBBNews】
〔AFP=時事〕(2021/05/25-13:49)
Study shows dogs can detect Covid-positive arrivals
Dogs can be trained to detect more than 90 percent of Covid-19 infections even when patients are asymptomatic, according to research published Monday, which authors hope could help replace the need to quarantine new arrivals.
Using their remarkable sense of smell -- which can pick up the equivalent of half a teaspoon of sugar in an olympic-sized swimming pool -- dogs have already shown that they can sniff out maladies such as cancer, malaria and epilepsy.
Several previous studies have shown proof-of-concept that dogs can detect SARS-CoV-2.
Researchers from the London School of Tropical Medicine wanted to see if dogs could detect a distinctive odour given off from chemical compounds associated with someone who is Covid positive but doesn't show symptoms.
They gathered samples of clothing and face masks from people who had tested positive for mild or symptomatic SARS-CoV-2.
Samples of the socks of 200 Covid-19 cases were collected and arranged in lab tests for six dogs that had been trained to indicate either a presence or absence of the chemical compound.
The dogs needed to be trained not to identify false positives in a bid to hack their reward system and obtain treats even if there were no Covid-19 samples in a given test.
This means that the dog fully understands and gets a reward for a correct negative as well as a correct positive, said Claire Guest, from the school's Faculty of Infectious and Tropical Diseases.
Overall, the dogs were successfully able to identify between 94 and 82 percent of SARS-CoV-2 samples.
The researchers then modelled how effectively these success rates, combined with traditional PCR tests, could help detect mild or asymptomatic Covid-19 cases.
They found that using dogs to screen arrivals at terminuses such as airports could detect 91 percent of cases, resulting in a 2.24 times lower rate of transmission than with PCR tests alone.
- 'Important start' -
Authors of the research, which has yet to be peer-reviewed, said they hoped it could eventually replace the need for travellers to quarantine -- which necessarily disrupts every arrival even though the vast majority are not Covid positive.
The key thing is that dogs are significantly quicker than other tests, said co-author James Logan.
What we're suggesting is that dogs would give the first initial screening, and then those (arrivals) that were indicated as positive would then receive a complimentary PCR test.
The team said that out of a plane full of arrivals -- around 300 people -- less than one percent were statistically likely to be carrying SARS-CoV-2.
Under current quarantine regulations employed by some countries, all 300 would need to isolate, causing significant inconvenience.
But given the sensitivity of trained dogs, a maximum of 35 people on board would be indicated as positive, the paper said.
Of these, only around 3 would be expected to return a positive PCR test.
This is a really important start and could lead to a useful, usable system, said Mick Bailey, professor of Comparative Immunology at the University of Bristol, who was not involved in the research.
But there's a lot more validation needs to be done before we could be confident that the dogs can reliably and specifically detect asymptomatic SARS-CoV-2 infection in people in airports and train stations.
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