米Ｊ＆Ｊ開発の新エボラワクチン、コンゴで来月から導入

【ジュネーブＡＦＰ＝時事】世界保健機関（WHO）は23日、エボラ出血熱の流行に見舞われているコンゴ民主共和国で来月から、米製薬・日用品大手ジョンソン・エンド・ジョンソン（J&J）が開発した新たなエボラワクチンが導入されると発表した。（写真は資料写真）
　ＷＨＯに対しては緊急医療援助団体「国境なき医師団（ＭＳＦ）」が、同国におけるワクチン支給が十分でないと非難したばかりだった。
　２０１８年８月に始まったコンゴ民主共和国のエボラ熱の流行では、死者数が２１００人以上に達し、２０１４年から１６年にかけて発生した西アフリカでの流行に次ぐ過去２番目の感染規模となっている。
　これまでにエボラ熱の感染地域に暮らす２２万３０００人以上が、独医薬品大手メルク製のワクチンを接種しているが、ＷＨＯは感染地域外の住民の予防接種のために、Ｊ＆Ｊが開発し実験段階にある２種類目のワクチンの使用を許可するよう同国政府を説得していた。
　Ｊ＆Ｊ製の新ワクチンについては、エボラ熱対応への不信感がはびこる地域で新薬を導入するのはリスクを伴うとして、前保健相のオリ・イルンガ氏が拒否していた。しかしイルンガ氏が７月に辞任した後、２番目のワクチン導入が承認される道筋が見えていた。
　同国保健省は２３日の声明で、エボラ熱の流行が続いた場合、メルク製ワクチンの在庫が切れるリスクが想定される点を指摘し、Ｊ＆Ｊのワクチンは予防手段として使用されると述べた。
　Ｊ＆Ｊの新ワクチンは１０月半ばに導入される見通しで、接種は５６日間を隔てて２回に分けて行われるという。【翻訳編集ＡＦＰＢＢＮｅｗｓ】
〔ＡＦＰ＝時事〕（2019/09/25-08:33）

The Democratic Republic of Congo will introduce a second Ebola vaccine next month, the World Health Organization said Monday, as a top medical charity accused the UN agency of rationing doses.
DRC's latest Ebola epidemic, which began in August 2018, has already killed more than 2,100 people in the country, making it the second deadliest outbreak of the virus, after the West Africa pandemic of 2014-2016.
Ebola fighters have been hindered by chronic insecurity in the affected provinces of eastern DRC, but much of the controversy surrounding the response has centred on the use of vaccines.
More than 223,000 people living in active Ebola transmission zones have received a vaccination produced by the pharma giant Merck.
WHO has for month been pushing the Kinshasa government to approve the use of a second experimental product, made by Johnson & Johnson, to protect those living outside of direct transmission zones.
The J&J vaccine had been rejected by DRC's former health minister Oly Ilunga, who cited the risks of introducing a new product in communities where mistrust of Ebola responders is already high.
But Ilunga's resignation in July appeared to pave the way for approval of the second vaccine.
WHO said in a statement that DRC planned to introduce the J&J product from mid-October.
This vaccine, which is given as a 2-dose course, 56 days apart, will be provided under approved protocols to targeted at-risk populations in areas that do not have active Ebola transmission as an additional tool to extend protection against the virus.
WHO Director-General, Tedros Adhanom Ghebreyesus, praised the latest decision by DRC authorities, who he said have once again shown leadership and their determination to end this outbreak as soon as possible.
- 'Rationing'? -
Doctors Without Borders, which has repeatedly criticised WHO's leadership of the Ebola response, levelled fresh criticism against the agency on Monday.
One of the main problems currently is the fact that, in practice, the (Merck) vaccine is rationed by the WHO and that too few people at risk are protected today, the charity known by its French acronym MSF said in a statement.
In an interview with AFP in July, MSF's international president Joanne Liu called on WHO to vaccinate whole villages where Ebola cases had emerged, rather than simply targeting the contacts of those infected.
The charity also renewed its complaints over the opaque management of the vaccine supplies by the World Health Organization.
MSF's efforts to expand access to vaccination ... have been frustrated by the tight controls on supply and eligibility criteria imposed by WHO, it said in a statement.
It's like giving firefighters a bucket of water to put out a fire, but only allowing them to use one cup of water a day, Natalie Roberts, MSF's emergency coordinator, said in a statement.
The charity also called for the creation of an independent international coordination committee to guarantee the transparency of the management of stocks and data sharing.
- 'Everything possible' -
WHO denied limiting the availability of the vaccine, saying it was doing everything possible to end the epidemic.
Along with the DRC government, no one wants to bring this epidemic to an end more than WHO, the agency's emergency director, Mike Ryan, said in a statement.
WHO is not limiting access to vaccine but rather implementing a strategy recommended by an independent advisory body of experts, Ryan added.
The WHO said last week that as of September 17, DRC had registered a total of 3,145 cases of Ebola since the outbreak began over a year ago, including 2,103 deaths.
It has declared the Ebola epidemic a public health emergency of international concern, a rare designation used only for the gravest epidemics.