ｉＰＳから骨格筋幹細胞　筋ジス治療に可能性―京大

　ヒトの人工多能性幹細胞（ｉＰＳ細胞）から筋肉の再生能力を持つ「骨格筋幹細胞」を作ることができたと、京都大ｉＰＳ細胞研究所などの研究チームが発表した。マウスに移植したところ、筋肉の収縮力が向上する効果が得られたという。
　研究チームは、全身の筋力が低下する難病の筋ジストロフィーの治療に生かせる可能性があるとしている。論文が３日、米科学誌ステムセル・リポーツ電子版に掲載される。（2020/07/03-01:09）

A Japanese team of researchers has produced muscle stem cells, which can regenerate muscles, from human induced pluripotent stem, or iPS, cells.
   The team, comprising researchers from institutes including Kyoto University's Center for iPS Cell Research and Application (CiRA), transplanted the cells into mice and confirmed an improvement in their muscle function. The technology could be effective in treating Duchenne muscular dystrophy, a disease that causes severe muscle degeneration, according to the team.
   An article on the study will be published in the online version of the U.S. science journal Stem Cell Reports on Friday.
   Muscle stem cells repair skeletal muscle tissues damaged through harsh exercise or other stimuli. The research team focused on two types of genes that appear in the repair process and was able to efficiently create muscle stem cells from iPS cells.
   The stem cells were inserted into the tibialis anterior leg muscles of mice with muscular dystrophy, and the team found that their muscle fibers recovered. The team also observed a slight improvement in power in the gastrocnemius leg muscle.